Contracts with the DIVAT biobank


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DIVAT/Centaure (DHOS/Inserm 2008)
Investigators GIRAL M, BROUARD S. (UMR643)
Study
 "One year validation of chronic rejection BIOMARKERS."*
La Charité Berlin
Investigators GIRAL M, DRAGUN D. (Berlin, Germany)
Study "Anti angiotensin II type I receptor and anti endothelin* and risk of acute rejection episode."
Institut de Recherche en Immunologie et Hématologie EA3948. Strasbourg
Investigators BAHRAM S, CARAPITO R. (Strasbourg, France)
Study "Genotype MICA and anti-MICA in incident patients since 1998."
GSK Laboratory
Investigators GIRAL M. (Nantes)
Study "Baff dosage in highly stable patients."
RISET Network (FP6)
Investigators BROUARD S. (Nantes)
Study "IP10 dosage in highly stable patients."
P. Halloran, (Edmonton, Canada)
Investigators RENAUDIN K. (Nantes)
Study "One year Kidney biopsies and correlation with chronic rejection biomarkers."
DIVAT/Centaure (DHOS/Inserm 2008)
Investigators GIRAL M, BROUARD S. (UMR643)
Study
 "One year validation of chronic rejection BIOMARKERS."*
M. Daha (Leiden university) / V. Fremeaux Bacchi (CHU pompidou)
Investigators GOSSELIN M. (Nantes)
Study "Complement analysis on Kidney biopsies with antibody mediated rejection."
DIVAT/Centaure network
Investigators GIRAL M, BROUARD S. (UMR643)
Study "CENTAURE 2010 (PAC 4) Validation of chronic rejection biomarker in “for cause” biopsies."

Additional programs


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INVESTIGATOR(S)
STUDY
Charreau B. Endothetical cell dysfunction in transplantation: from mechanisms to prevention
Bonneville M, Brouard S, Soulillou JP. Unravelling cellular and molecular mechanisms in chronic "antibody-mediated" rejection
Brouard S. Validation of blood diagnostic markers of graft survival
Chiffoleau E, Brouard S. Characterizing the function of new molecules
Brouard S. Analysis of B-cell frequency and function in C-ABMR and GVHD
Giral M. CNI Weaning
Giral M. Telemedecine - economic medical economic study - kidney transplanted patients monitoring
Pattier S. Biocollection DIVAT-coeur
Magnan A, Perigaud C. Clinic organ transplantation activity reinforcement
Bonnaud-Antignac A, Tessier P. Social and Human Sciences in Transplant Sciences
Halary F, Imbert BM. Transplantation and infection
Dantal J, Dreno B, Halary F. Transplantation and cancer
Dantal J. Original disease / initial desease reoccurence on graft
Magnan A Thoracic transplantation: organ transplant activity reinforcement

Institutional contracts


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2010 - WEANING
Principal investigator Giral M. (ITERT)
Study "Prospective randomised open-labelled multicentric parallel controlled phase IV study of Calcineurin Inhibitors weaning in selected long term kidney recipients. A validation of biomarkers of risk in transplantation." (2)
Sponsor
 PHRC National
Grant 490 K€
2009 - DIVAT-URO
Principal investigator Karam G. (Urologie)
Study "Extension de la cohorte DIVAT (Données Informatisées et Validées en Transplantation) aux paramètres chirurgicaux et urologiques des transplantés rénaux et pancréatiques." (1)
Sponsor
 PHRC National
Grant 130 K€
2008 - VALBIO 12
Principal investigator Giral M. (ITERT)
Study "Validation de marqueurs phénotypiques et transcriptionnels du rejet chronique dans une étude prospective un an après transplantation." (2)
Sponsor
 DHOS Inserm
Grant 80 K€
2007 - PANVIRUS
Principal investigator Giral M. (ITERT)
Study "Dépistage sur puce oligonucléotidique panvirale de virus émergents chez le sujet immunosupprimé après transplantation rénale ou pancréatique." (1)
Sponsor
 PHRC National
Grant 180 K€
2005 - DPRC ARRAY
Principal investigator Soulillou JP. (ITERT)
Study "Evaluation d’un test de dépistage précoce du rejet chronique et de l’état de tolérance opérationnelle par MicroArray en transplantation rénale." (1)
Sponsor
 PHRC National
Grant 308 K€
2003 - RETIA*
Principal investigator Soulillou JP. (ITERT)
Study "Evaluation d’un test de dépistage précoce du rejet chronique et de l’état de tolérance opérationnelle par MicroArray en transplantation rénale." (1)
Sponsor
 PHRC National
Grant 308 K€

National grant obtained by collaboration of the DIVAT network partners:

- (1) = whole network

- (2) = a part of the network

* Publications: published or submitted

Collaboratives studies


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CHU Nantes
DIVAT Nantes / HUGO "Prophylaxie anti-CMV par valganciclovir contre abstention thérapeutique chez les greffés rénaux à risque intermédiaire de maladie à CMV : recueil rétrospectif au sein des CHU membres de la société de néphrologie de l'Ouest."
PI Boulay H.
DIVAT Network "Kidney Transplant Failure Score (Time dependant ROC)."
PI Foucher Y.
DIVAT Network "Relative survival tranplanted / general population." *
PI Akl A.
DIVAT Network "Semi Markov analysis." *
PI Foucher Y.
DIVAT Network / REIN Network "Relative survival transplanted / dialysed population."
PI Giral M.
DIVAT Network / Novartis Lab. "Relative survival second graft / first graft." *
PI Dantal J.
DIVAT Network / BMS Lab.
 "European economic impact of kidney transplantation." *
PI Giral M.
DIVAT Network "Pneumocystis risk factors." *
PI Lavainne F.
CHU Lyon
DIVAT Network "Etude du rôle du groupe sanguin sur la survenue de thrombose artérielle du greffon rénal."
PI Thaunat O.
CHU Nancy
DIVAT Network "Pre-emptive transplantation." *
PI Kessler M.
DIVAT Network "Demographic characteristics of DIVAT" *
PI Ladrière M.
CHU Montpellier
DIVAT Network "Anemia risk factor analysis" *
PI Garrigue V.
CHU Toulouse
DIVAT Network "C hepatitis and patient survival" *
PI Kamar N.
CHU Paris - Necker


PI = Principal Investigator

* = Publications published, submitted or in preparation

DIVAT Network "Analyse des troisièmes greffes."
PI Legendre C.
DIVAT Network "Delayed graft function score (ROC analysis)."
PI Legendre C.
DIVAT Network "Retrospective analysis of focal glomerular sclerosis recurrence after transplantation." *
PI Legendre C.

Industrial contracts


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Cellcept/Azathioprin
Principal investigator
 Giral M.
Roche Lab.
Contract current status Approved
Second graft survival analysis (relative survival)
Principal investigator
 Dantal J.
Partial financing Novartis Lab.
Contract current status Approved
Rapamycin adverse events registry
Principal investigator
 Blancho G.
Partial financing Pfizer Lab.
Contract current status Approved
Economic impact of Transplantation in Europe
Principal investigator
 Giral M.
Partial financing BMS Lab.
Contract current status On going
Score of Delayed graft function
Principal investigator
 Legendre C.
Partial financing Genzyme Lab.
Contract current status On going

Plus d'articles...

  1. Industrial contracts (2)
  2. Scientific projects